Saturday, 31 December 2022 13:33

KAPPAREST - Supplement inhibiting the inflammation-promoting factors

Twenty years ago, and you would have been ahead of your time, and part of the minority of the educated few who spend their days researching such things.


A decade ago, and things were beginning to shift with a greater general awareness, and now in the 2020’s it is commonly understood that inappropriate INFLAMMATION is the underlying cause of a majority of all degenerative diseases from heart disease and cancer to arthritis and neurological diseases such as parkinson’s disease and dementia.

Inflammation is the epigenetic factor (Epigenetic changes are modifications to DNA that regulate whether genes are turned on or off) that activates the genes that dispose us to these conditions, and it has many different sources.

However, a significant source is generated by changes in our gastrointestinal tract (GIT) and how effectively our liver handles everyday metabolic, endogenous and exogenous toxins. The food we eat impacts our GIT microbiota (the bacterial and other microbial residents within our gut) and microbiome (the collective genomes of the microbes (composed of bacteria, bacteriophage, fungi, protozoa and viruses) that live inside and on the human body).

The further away we move from a diverse wholefood diet and the closer we move to a narrow, processed food (PF) or ultra-processed food (UPF) diet, the more we are likely to promote inappropriate inflammation from within the GIT. This will magnify any risk and disposition we may have to the common killers of heart disease, stroke, cancer, dementia and auto-immune diseases that are so ubiquitous and progressive.

In other words, a UPF diet increases the risk of diet-related inflammation generated non-communicable diseases (NCDs)

Noncommunicable diseases (NCDs), also known as chronic diseases, tend to be of long duration and are the result of a combination of genetic, physiological, environmental and behavioural factors

In a 2018 study of nineteen European countries’ consumption of UPFs per household, the UK was top of the table at a whopping 50.4%, with each percentage point increase in the household availability of UPFs resulting in an increase of 0.25 percentage point in obesity prevalence.

The inevitability of excessive inflammation either directly from UPFs or from the consequences of inflammation needs to be addressed. The first obvious step is to omit all UPFs and as much processed foods as possible and revert to a wholefood diet. The focus needs to be on good quality, organic, pasture fed animal protein, whole fresh and organic vegetables and a moderate to small portion of carbohydrates preferably from wholefood sources such as sweet potato, quinoa, buckwheat or rice.

The next step is to select a food supplement that can provide therapeutic anti-inflammatory actions. It can be very challenging to achieve this even with an optimal diet and it is very helpful to have the required nutrients in a convenient form that helps to guarantee daily intake.

It also makes sense to call on the wisdom of traditional plant-sourced ingredients most of which have been used for thousands of years for their health benefits. KappArest (Biotics Research) is the name of my most favoured anti-inflammatory supplement.

It provides 10 plant extracts / naturally-occurring nutrients all of which have been shown in various trials and studies to reduce molecules of inflammation called cytokines and which are mediated by the ancient innate immune transcription factor found in most human cells called NF-kB (Nuclear Factor Kappa-B, hence the name of the supplement) and which is recognised as a therapeutic target of intervention in a range of inflammatory conditions.

NF-κB likely plays the most prominent role in the development and function of the immune system, oxidative stress and genotoxic injury and, not surprisingly, when dysregulated, contributes to the pathophysiology of inflammatory disease.

The 10 ingredients are the extracts of whole Curcuma Longa, which is also fully emulsified for enhanced absorption into the body, Boswellia serrata, Bee Propolis, Green Tea, Ginger (Zingiber officinalis), Rosemary (Rosemarinus officinalis), Celery seed (Apium graveolens), Phytolens (Lens esculenta) which is from lentil husk, alpha-lipoic acid and trans-resveratrol.

The mix of proven anti-inflammatory ingredients abides by one of the tenets of nutrition which is that of synergy; the sum of the whole is great than the sum of the parts

Each natural extract exerts anti-inflammatory effects on a range of inflammatory cytokines. In fact, combined for all of these plant extracts, there are tens of thousands of peer reviewed journal articles that explore, discuss and describe their potential health benefits.

Client after client has helped to show me the efficacy of this specific anti inflammation food supplement in clinical practice on a consistent basis. From simple issues such as connective tissue disorders including small joint arthritis, back ache, muscular aches and pains, to digestive disorders such as Ulcerative Colitis and Crohn’s Disease, and nerve pain conditions, I have observed clients experience notable amelioration of their symptoms.

Each case is an anecdote, because they are not part of any formal trial, but when the anecdotes number in their hundreds this turns into useful and practical experiential data.

With over twenty years of experience recommending KappArest to my clients, it’s stood the test of time and long may it continue to be available for future clients.

  • TikTok in the Light of Congressional Pressur
    TikTok in the Light of Congressional Pressur

    Recent actions by Congress aimed at pressuring the Chinese owner of TikTok, ByteDance, have sparked much debate and uncertainty among millions of users and businesses using the popular app. The new bill, part of a $95 billion foreign aid package, puts ByteDance under pressure to sell TikTok within a year, otherwise facing financial penalties. However, while the bill's objective seems clear, numerous doubts and questions arise regarding the consequences and effectiveness of such actions.

    Written on Saturday, 20 April 2024 12:14 in Internet Read more...
  • Unique Dining Experience in Verona
    Unique Dining Experience in Verona

    In today's fast-paced world, where technology increasingly dominates our daily interactions, Al Condominio restaurant in the picturesque city of Verona has decided to go against the tide by offering its guests a unique gastronomic experience. It's not just another dining establishment but a true oasis of direct communication and genuine relationships.

    Written on Tuesday, 16 April 2024 16:36 in Internet Read more...
  • Father Took His Son to Court - A Dramatic Story from Turin
    Father Took His Son to Court - A Dramatic Story from Turin

    An extraordinary yet ambiguous story unfolded in the charming city of Turin, where a thirty-year-old man, despite reaching adulthood, not only avoided steady employment but also refused to leave the family nest. The father's decision, concerned about his son's passivity and lack of independence, to take him to court sparked a wave of discussions about family relationships and adult life.

    Written on Saturday, 13 April 2024 10:07 in Economy Read more...
  • The mysterious story of the Renaissance thaler of Saxon dukes discovered in the vicinity of Duniewo
    The mysterious story of the Renaissance thaler of Saxon dukes discovered in the vicinity of Duniewo

    In recent days, the St. Cordula Association received an extraordinary report from the vicinity of Duniewo in the West Pomeranian Voivodeship. During routine agricultural work, one of the local farmers, losing a part of his plow, stumbled upon a silver coin, which turned out to be a Renaissance thaler of Saxon dukes. This exceptional find sheds new light on the history of these lands and their connections to distant times.

    Written on Tuesday, 09 April 2024 15:25 in Exchange Read more...
  • Heathrow Incident - Collision of British Airways and Virgin Atlantic Planes
    Heathrow Incident - Collision of British Airways and Virgin Atlantic Planes

    Yesterday, an unusual event occurred at Heathrow Airport - a collision between planes belonging to British Airways and Virgin Atlantic. Despite the potentially dangerous situation, both airlines and airport staff quickly responded, minimizing the impact of the incident.

    Written on Saturday, 06 April 2024 19:38 in Company Read more...
  • Southeast Asia’s Consumer Backlash - Major Brands Face Boycotts
    Southeast Asia’s Consumer Backlash - Major Brands Face Boycotts

    In the wake of the Gaza conflict, consumers in Southeast Asia, particularly in Indonesia and Malaysia, are taking a stand by boycotting major international brands such as McDonald’s and Starbucks. Despite assertions from local franchise owners about their independence from political issues tied to Israel, the boycotts are making a significant impact, reflecting the potent influence of global events on local consumer behavior.

    Written on Wednesday, 20 March 2024 10:40 in Business Read more...
  • Bali Battles Environmental Crisis as Beaches Overflow with Waste
    Bali Battles Environmental Crisis as Beaches Overflow with Waste

    Bali, once a symbol of untouched natural beauty and a beacon for travellers seeking solace in its lush landscapes and serene beaches, now faces a daunting environmental crisis. The picturesque shores, especially those of Kedonganan Beach, are increasingly marred by the scourge of plastic waste. This distressing situation is a result of both the booming tourism industry and insufficient waste management practices, putting Bali’s reputation as a paradise island at risk.

    Written on Wednesday, 20 March 2024 10:26 in Company Read more...
  • UK Battles Against Emerging Synthetic Drug Threat
    UK Battles Against Emerging Synthetic Drug Threat

    The UK is currently grappling with the rise of powerful synthetic drugs known as nitazenes, sparking significant concern among health professionals and law enforcement agencies. The National Crime Agency (NCA) has reported over a hundred deaths linked to these substances since last summer. Experts like Dr. Mark Pucci argue that the UK's system for tracking and responding to the spread of these drugs is insufficient, leading to a likely underestimation of the true scale of the issue.

    Written on Wednesday, 20 March 2024 10:08 in Work Read more...